
The Final Frontier of Drug Delivery: Navigating the Blood-Brain Barrier
The next generation of CNS therapies will depend on crossing the blood-brain barrier safely, selectively, and at therapeutic scale.


In this interview, Jonathan Bush, CEO of Zus Health and co-founder of Athenahealth, discusses how artificial intelligence can address fundamental problems in the U.S. healthcare system, focusing on automating administrative tasks and the need to break established rules to foster innovation.
“The real opportunity lies in automating the mundane administrative work plaguing the system.”“We need more people willing to break the rules and challenge the status quo to achieve true innovation in healthcare.”
Jonathan Bush emphasizes that achieving real transformation in healthcare requires a pragmatic approach that uses technology to solve concrete, everyday problems rather than pursuing only grand innovations.

The next generation of CNS therapies will depend on crossing the blood-brain barrier safely, selectively, and at therapeutic scale.

Even the strongest science does not guarantee an investable asset. Here, we discuss how to align early-stage discovery programs for small molecules with investor expectations in a complex biotech funding environment.
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